Analytical Testing Procedure for aluminum foil, specifically designed for the secure packaging of drug products. This analytical-grade foil ensures optimal protection against moisture, light, and air, preserving the integrity and efficacy of your pharmaceuticals. Its superior barrier properties and compliance with industry standards make it an ideal choice for pharmaceutical applications, ensuring that your products remain safe and effective throughout their shelf life. Choose our aluminum foil for reliable, efficient, and safe packaging solutions that meet the rigorous demands of the healthcare industry.

Analytical Method for Aluminum Foil

1.0     Description:

• • Check the samples against the current approved standard for Design, Colour, Printing and printed text matter.

• • Crush the foil with hand, cracking noise indicating that the foil is tampered.

For detailed Description Test Procedure – Refer GTP – Description / Appearance Test.

2.0     Thickness with LDPE:

• • Cut a piece of 5x 5 cm² or 10×10 cm² of blister foil with the help of scissors or sharp knife.

• • Weigh the piece and calculate the thickness using the given below formula.

Weight in mg

                     Thickness in mm           =—————————————————————-

(Length x width in mm) x 0.0027.

3.0     Thickness without LDPE:

• • Cut a piece of 5x 5 cm² or 10×10 cm² area accurately of Aluminum foil being examined by using a pair of scissors or knife .

• • Place the sample in the Toluene beaker and heat on a water bath for 30 minutes and dry with the help of tissue paper. Weigh it.

• • Than measure the thickness with the help of Screw Gauge  Or given below formulae.

Weight in mg

                       Thickness in mm           =—————————————————————-

(Length x width in mm) x 0.0027      

4.0     Width of Aluminum Foil

• • Check the width of the reel samples by measuring the dimension in transverse direction using a scale and record the observation.

5.0     Grammage of Aluminum Foil:

• • Cut a piece of 5×5 cm² or 10x10cm² of Aluminum foil being examined by using a   scissors or knife.

• • Weigh the piece and record its weight in gm (A gm).

• • Place the sample in the Toluene beaker and heat on a water bath for 30 minutes and dry with the help of tissue paper. Weigh it .

• • Repeat the same process till the constant weight. Weigh the piece and record its weight in gm (B gm).

• • Carry out the same procedure for remaining four pieces of Aluminum foil.

• • Calculate the GSM by using following Calculation.

Weight of piece (A gm)x100x100

          Total Grammage of Aluminum foil   =———————————————————–

Size of piece in cm (5×5 or 10×10)

Weight of piece (B gm)x100x100

                 Grammage of Aluminum foil  =———————————————————–

Size of piece in cm (5×5 or 10×10)

Weight of piece (A-B gm)x100x100

               Grammage of LDPE     =———————————————————–

Size of piece in cm (5×5 or 10×10)

6.0     Repeat Length:

• • Measure the text repeat length with the help of scale and record the observation.

7.0     Text Matter Review:

• • Check the text matter with the help of approved artwork.

8.0     Ink Lifting of Aluminum Foil:

• • Stick a piece of cello tape (about 3 inch) on the printed surface of the foil.

• • Leave it for about a minute.

• • Pull out the tape.

• • The printed matter should not be peel off along with the tape and there should not be any distortion of printing matter on the foil.

9.0     Pinholes Test of Aluminum Foil:

• • Collect a full web width sample of approximate one meter in length.

• • Place the sample on the glass platform of the unit then close the upper part of the unit.

• • Switch on the unit to glow the lamp.

• • Observe the sample all area, starting from end to another end of the sample.

• • Count the number of pinholes in the sample Pinhole shall be recorded as number of pinholes per square meter in the visual inspection report.

10.0    Machine Suitability of of Aluminum Foil:

• • Take the trial run of foil and check the sealing and appearance of strip. Sealing should be proper.

11.0    Visual Inspection of of Aluminum Foil:

• • Check the foil for proper packing and cleanliness.

• • The foil roll should be properly packed with polythene and it should be clean.